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Clostridium tertium : ウィキペディア英語版
Clostridium tertium

''Clostridium tertium'' is an anaerobic, motile, gram-positive bacterium. Although it can be considered an uncommon pathogen in humans, there has been substantial evidence of septic episodes in human beings. C. ''tertium'' is easily decolorized in Gram-stained smears and can be mistaken for a Gram-negative organism.〔Steyaert S, Peleman R, Vaneechoutte M, De Baere T, Claeys G, Verschraegen G, (1999). "Septicemia in Neutropenic Patients with ''Clostridium tertium'' Resistant to Cefepime and Other Expanded-Spectrum Chephalosporins." ''Journal of Clinical Microbiology'' 37(11):3778-3779.〕 However, ''C.'' ''tertium'' does not grow on selective media for Gram-negative organisms.〔
==History==
''C.'' ''tertium'' was initially isolated from war wounds by Captain Herbert Henry (RAMC) in 1917, but it was not until the first human cases of ''C.'' ''tertium'' bacteremia were reported in 1963 that it was recognized as a human pathogen.〔Miller DL, Brazer S, Murdoch D, Barth Reller L, Corey GR, (2001). "Significance of ''Clostridium tertium'' Bacteremia in Neutropenic and Nonneutropenic Patients: Review of 32 Cases." ''Brief Reports CID'' 2001:32.〕 ''C.'' ''tertium'' has been isolated in neutropenic and nonneutropenic patients, and in cases of necrotizing fasciitis and gangrene.〔Seol B, Gomercic MD, Naglic T, Gomercic T, Galov A, Gomercic H (2006). "Isolation of ''Clostridium tertium'' from a Striped Dolphin (''Stenella coeruleoalba'') in the Adriatic Sea." ''Journal of Wildlife Diseases'' 42(3):709-711.〕 It has also been recognized as a causative agent of enteritis in cattle, but it is an uncommon human pathogen.〔 ''C.'' ''tertium'' has also been isolated from soil and from faeces of healthy neonates and infants.〔

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